Research & Development
Where innovation becomes impact
At Oncovara Pharmaceuticals, research is more than a function it's the heartbeat of our mission,As a next generation oncology startup.
Oncovara’s R\&D efforts are laser-focused on creating breakthrough therapies that address some of the most aggressive and treatment resistant cancers known today.
We don’t follow trends we forge new scientific frontiers.
Our Scientific Approach
Our integrated R\&D platform combines:
Novel small molecule discovery targeting previously “undruggable” cancer drivers
Structure based drug design and medicinal chemistry
AI enhanced screening for optimised compound selection
Biomarker driven development to improve precision and predictability
Translational oncology models to bridge lab data to patient response
This approach allows us to rapidly translate ideas from target validation to preclinical efficacy accelerating timelines while maintaining scientific rigor.
Inventing Tomorrow’s Therapies
We’ve already discovered and validated multiple proprietary molecular entities (NMEs),with mechanisms of action that target:
Tumor microenvironment modulation**
Oncogenic signaling suppression**
Epigenetic reprogramming**
Drug-resistance pathways**
Our lead candidate, OVX 101,is advancing toward IND-enabling studies with promising efficacy across multiple resistant solid tumors.
R\&D Pillars
1. Targeted Innovation
We design drugs with precision — focusing on specific genetic, molecular, or immune pathways that drive tumor survival and progression.
2. Preclinical Excellence
Our models replicate complex tumor biology, giving us meaningful data before we ever reach the clinic.
3. Smart Risk Taking
We pursue bold ideas grounded in validated science — taking calculated risks where innovation can yield transformative therapies.
4. Data-Driven Decisions
Our AI powered analytics platform integrates multi omics data, optimising compound selection, dosing strategies, and patient stratification.
